Methylhydrazine → (E)-(2,4,6-trifluorophenyl)methylidenehydrazine
반응식
[F:1][C:2]1[CH:9]=[C:8]([F:10])[CH:7]=[C:6]([F:11])[C:3]=1[CH:4]=O.C[NH:13][NH2:14]>CCOCC>[F:1][C:2]1[CH:9]=[C:8]([F:10])[CH:7]=[C:6]([F:11])[C:3]=1/[CH:4]=[N:13]/[NH2:14]참가 물질
4
실험 절차
2,4,6-Trifluoro-benzaldehyde (x) (4.5 g, 27.3 mmol) was dissolved in Et2O, methylhydrazine was added (1.43 mL, 27.3 mmol) and the RM was stirred overnight. The solvent was evaporated and the solid residue was suspended in a mixture of pentane and EtOAc to afford after filtration the title compound as a bright yellow crystalline solid (tR 4.95 min (conditions 3), MH+=198.1).
후처리
- customThe solvent was evaporated
- additionthe solid residue was suspended in a mixture of pentane and EtOAc
- customto afford
- filtrationafter filtration the title compound as a bright yellow crystalline solid (tR 4.95 min (conditions 3), MH+=198.1)
출처 및 근거
- ORD 기록
- ord-cd338e979c4d47d48408e78b4dc0922f
- 출처 데이터셋
- uspto-grants-2014_09
- 특허 번호
- US08822468B2
반응 노트
불러오는 중…