Triphenylphosphine → HCID 178453006, 화합물

HRID 70366

반응식

HRID 70366 반응식
O[CH2:2][C:3]1[NH:4][C:5]([NH:8][C:9](=[O:15])[O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[N:6][N:7]=1.[NH2:16][C:17]1[CH:22]=[C:21]([Cl:23])[CH:20]=[CH:19][C:18]=1[SH:24].C1C=CC(P(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.CC(OC(/N=N/C(OC(C)(C)C)=O)=O)(C)C>C(Cl)Cl>[NH2:16][C:17]1[CH:22]=[C:21]([Cl:23])[CH:20]=[CH:19][C:18]=1[S:24][CH2:2][C:3]1[NH:4][C:5]([NH:8][C:9](=[O:15])[O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[N:6][N:7]=1

참가 물질

6

반응물 4

HCID 11776TriphenylphosphineHCID 120002-Amino-4-chlorobenzenethiolHCID 6034084Di-tert-butyl diazene-1,2-dicarboxylateHCID 178453005HCID 178453005, 화합물

생성물 1

HCID 178453006HCID 178453006, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

A solution of tert-butyl (5-(hydroxymethyl)-4H-1,2,4-triazol-3-yl)carbamate (190 mg, 0.888 mmol), 2-amino-4-chlorobenzenethiol (213 mg, 1.332 mmol), PPh3 (466 mg, 1.776 mmol) and di-tert-butylazodicarboxylate (409 mg, 1.776 mmol) in CH2Cl2 (10 ml) was stirred at room temperature for 2 days. The solvent was then removed and the crude residues was loaded on silica gel column to get the title compound.

후처리

  1. customThe solvent was then removed

출처 및 근거

ORD 기록
ord-26e7f3bb0d004fe48de4f7eeeebe439b
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08822530B2

연결된 노트

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