반응식
[Br-].[CH2:2]([P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[Li]CCCC.[CH3:34][C:35]([CH3:42])=[CH:36][CH2:37][CH2:38][C:39](=O)[CH3:40]>>[CH3:40][C:39]([CH2:38][CH2:37][CH:36]=[C:35]([CH3:42])[CH3:34])=[CH:2][CH2:3][C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1참가 물질
4
실험 절차
Starting from phenethyltriphenylphosphonium bromide (3.48 g, 7.78 mmol, 1.0 equiv.), n-BuLi (1.6 M in hexanes, 4.9 mL, 7.78 mmol, 1.0 equiv.) and 6-methylhept-5-en-2-one (1.48 g, 11.7 mmol, 1.5 equiv.), 0.29 g (17%) of the title compound as a colorless oil was obtained after purification by flash chromatography on SiO2 (cyclohexane).
출처 및 근거
- ORD 기록
- ord-98f93d6b988d4c6b80eea9dbff336a80
- 출처 데이터셋
- uspto-grants-2015_11
- 특허 번호
- US09193935B2
연결된 노트
불러오는 중…