Hydrochloric Acid → HCID 68815119, 화합물

HRID 732553노트

반응식

HRID 732553 반응식
C[O:2][C:3](=[O:24])[C:4]1[CH:16]=[C:15]([C:17]([C:19]2[O:20][CH:21]=[CH:22][CH:23]=2)=[O:18])[CH:14]=[C:6]([C:7]([N:9]([CH3:13])[CH2:10][CH2:11][CH3:12])=[O:8])[CH:5]=1.[OH-].[Na+].Cl>CO>[O:20]1[CH:21]=[CH:22][CH:23]=[C:19]1[C:17]([C:15]1[CH:14]=[C:6]([C:7]([N:9]([CH3:13])[CH2:10][CH2:11][CH3:12])=[O:8])[CH:5]=[C:4]([CH:16]=1)[C:3]([OH:24])=[O:2])=[O:18]

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 68816228HCID 68816228, 화합물

생성물 1

HCID 68815119HCID 68815119, 화합물

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

Dissolve 5-(furan-2-carbonyl)-N-methyl-N-propyl-isophthalamic acid methyl ester (100 mg, 0.3 mmol) in methanol (10 mL). Add dropwise 2 N NaOH (0.225 mL) and stir overnight at room temperature. Acidify the mixture to about pH=6 by 5 N HCl and concentrate to near dryness. Dilute the residue with ethyl acetate and wash by saturated aqueous sodium chloride solution, dry (magnesium sulfate) and concentrate.

후처리

  1. concentrationconcentrate to near dryness
  2. additionDilute the residue with ethyl acetate
  3. washwash by saturated aqueous sodium chloride solution
  4. dry with materialdry (magnesium sulfate)
  5. concentrationconcentrate

출처 및 근거

ORD 기록
ord-9f394280178a4929805434abb9a969bf
출처 데이터셋
uspto-grants-2009_09
특허 번호
US07585885B2

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