alpha-Hydroxyacetophenone → Flavonol

HRID 742080

반응식

HRID 742080 반응식
[C:1]1(C2C=CC=CC=2)[CH:6]=[CH:5][C:4]([CH:7]=[O:8])=[CH:3][CH:2]=1.[OH:15][CH2:16][C:17]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)=[O:18]>C(O)C.[OH-].[Na+]>[OH:15][C:16]1[C:7](=[O:8])[C:4]2[C:3](=[CH:2][CH:1]=[CH:6][CH:5]=2)[O:18][C:17]=1[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

참가 물질

5

반응물 2

HCID 68490alpha-HydroxyacetophenoneHCID 76689(1,1'-Biphenyl)-4-carboxaldehyde

생성물 1

HCID 11349Flavonol

시약·촉매·용매 2

HCID 702Ethanol용매2회HCID 14798Sodium Hydroxide용매2회

실험 절차

180 mg of 4'-vinyl, 4-biphenyl aldehyde was mixed with 0.3 ml of 2-hydroxyacetophenone in 30 ml of ethanol. In a separate flask, 2.0 gms of NaOH was dissolved in 10 ml of aq. ethyl alcohol (50%). An NaOH solution was slowly added to the aldehyde solution. The resulting solution slowly changed its color from green to yellow to dark red. The rest of the reaction was carried out according to the method described in Example 1(b) above, producing 4'styryl, 3-hydroxyflavone.

출처 및 근거

ORD 기록
ord-21ed05cb9ada411cb768795976d60d3f
출처 데이터셋
uspto-grants-1996_09
특허 번호
US05552551

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