Alpha-Aminobutyric Acid → 2-(Acetylamino)butanoic acid

HRID 7535

반응식

HRID 7535 반응식
[NH2:1][CH:2]([CH2:6][CH3:7])[C:3]([OH:5])=[O:4].[C:8](OC(=O)C)(=[O:10])[CH3:9]>C(O)(=O)C>[C:8]([NH:1][CH:2]([CH2:6][CH3:7])[C:3]([OH:5])=[O:4])(=[O:10])[CH3:9]

참가 물질

4

반응물 2

HCID 6657Alpha-Aminobutyric AcidHCID 7918Acetic Anhydride

생성물 1

HCID 3061072-(Acetylamino)butanoic acid

시약·촉매·용매 1

HCID 176Acetic Acid용매

반응 조건

온도
100 °C

실험 절차

163 g (1.58 mol) 2-aminobutanoic acid are dissolved in acetic acid, and 242 g (2.37 mol) acetic anhydride are added dropwise. The mixture is stirred for 2 h at 100° C. until completion of reaction, then the solution evaporated to dryness in vacuo. The solid residue is suspended in ethyl acetate, filtered and washed with diethyl ether.

후처리

  1. customthe solution evaporated to dryness in vacuo
  2. filtrationfiltered
  3. washwashed with diethyl ether

출처 및 근거

ORD 기록
ord-4825907718a34102b76de664069c39ba
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07087605B2

연결된 노트

불러오는 중…