Benzyl Isothiocyanate → 1,5-Di(benzylthiocarbamoylamino)naphthalene

HRID 758

반응식

HRID 758 반응식
[C:1]1([NH2:12])[C:10]2[CH:9]=[CH:8][CH:7]=[C:6]([NH2:11])[C:5]=2[CH:4]=[CH:3][CH:2]=1.[CH2:13]([N:20]=[C:21]=[S:22])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C(OCC)(=O)C>[CH2:13]([NH:20][C:21]([NH:12][C:1]1[C:10]2[C:5](=[C:6]([NH:11][C:21](=[S:22])[NH:20][CH2:13][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1)=[S:22])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

참가 물질

4

반응물 2

HCID 2346Benzyl IsothiocyanateHCID 167201,5-Diaminonaphthalene

생성물 1

HCID 196932801,5-Di(benzylthiocarbamoylamino)naphthalene수율 30.7%

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

반응 조건

온도
80 °C

실험 절차

1,5-Naphthalenediamine (0.791 g, 5 mM) was dissolved in 20 ml of ethyl acetate, and 2 equivalents of benzylisothiocyanate (1.492 g, 10 mM) were added. The mixture was stirred at 80° C. for 30 minutes. After cooling, the reaction mixture was filtered, and washed with ethylacetate/n-hexane to obtain 0.70 g (30.7% yield) of a colorless crystal of compound A-29.

후처리

  1. temperatureAfter cooling
  2. filtrationthe reaction mixture was filtered
  3. washwashed with ethylacetate/n-hexane

출처 및 근거

ORD 기록
ord-d421bcbbd72f4cb18c2bcf8464545117
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05723075

연결된 노트

불러오는 중…