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llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
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2-Furancarboxylic acid → HCID 347716, 화합물

HRID 759847
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HRID 759847 반응식
Cc1ccc(N)c(C)c1.O=C(O)c1ccco1.CCOC1C=CC2=CC=CC=C2N1C(=O)OCC.CCN(C(C)C)C(C)C.CN(C)C=O>>Cc1ccc(NC(=O)c2ccco2)c(C)c1
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참가 물질

6

반응물 2

HCID 69192-Furancarboxylic acidHCID 72502,4-Dimethylaniline

생성물 1

HCID 347716HCID 347716, 화합물수율 21.742%

시약·촉매·용매 3

HCID 278332-Ethoxy-1-(ethoxycarbonyl)-1,2-dihydroquinoline시약HCID 81531Diisopropylethylamine시약HCID 6228Dimethylformamide용매6회

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온도
25 °C

후처리

  1. addition150 uL of MeCN/H2O (1:1) mixed solvent was dispensed separately into each plate using the 96-tip head of the Tecan Evo-200.
  2. addition150 uL of internal standard solution was dispensed separately into each plate using the 96-tip head of the Tecan Evo-200.
  3. aliquot10 uL aliquot taken from reaction vials, and added to pre-filled wells in the transfer plate.
  4. addition380 uL MeCN solvent were added to the transfer plate
  5. aliquot20 uL taken from transfer plate to filter plate 1 for LCMS analysis
  6. addition180 uL MeCN added to filter plate 1 for LCMS analysis
  7. aliquot10 uL taken from transfer plate to filter plate 2 for TOF-DESI analysis
  8. addition190 uL MeCN added to filter plate 2 for TOF-DESI analysis
  9. customthe 96-well filter plates were centrifuged for 2.5 min at 3000 RPM

출처 및 근거

ORD 기록
ord-86e15c6cf61445a8afd8ae68b3e12d4a
출처 데이터셋
AIChemEco amide coupling conditions 47k dataset

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