Dimethyl Sulfoxide → 2-(2,1,3-benzothiadiazol-5-ylamino)-8-cyclopentyl-6-(2,6-dichlorophenyl)-8H-pyrido[2,3-d]pyrimidin-7-one

HRID 809840노트

반응식

[CH3:1][C:2]([CH3:3])([O-:4])[CH3:5].[CH3:45][S:46]([CH3:47])=[O:48].[CH3:50][CH2:51][O:52][C:53](=[O:54])[CH3:55].[CH:7]1([n:12]2[c:13](=[O:34])[c:14](-[c:26]3[c:27]([Cl:33])[cH:28][cH:29][cH:30][c:31]3[Cl:32])[cH:15][c:16]3[c:17]2[n:18][c:19]([S:22]([CH3:23])(=[O:24])=[O:25])[n:20][cH:21]3)[CH2:8][CH2:9][CH2:10][CH2:11]1.[K+:6].[OH2:49].[n:35]1[s:36][n:37][c:38]2[c:39]1[cH:40][cH:41][c:42]([NH2:44])[cH:43]2>>[CH:7]1([n:12]2[c:13](=[O:34])[c:14](-[c:26]3[c:27]([Cl:33])[cH:28][cH:29][cH:30][c:31]3[Cl:32])[cH:15][c:16]3[c:17]2[n:18][c:19]([NH:44][c:42]2[cH:41][cH:40][c:39]4[n:35][s:36][n:37][c:38]4[cH:43]2)[n:20][cH:21]3)[CH2:8][CH2:9][CH2:10][CH2:11]1