Dimethyl Sulfoxide → 4-(2-Amino-4-methoxy-benzothiazol-7-yl)-1-methyl-piperazin-2-one
반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH2:14][CH2:13][N:12]([CH3:15])[C:11](=[O:16])[CH2:10]2)=[CH:5][C:4]=1[NH:17][C:18]([NH2:20])=[S:19].Br.CC(O)=O.CS(C)=O>CC(O)=O>[NH2:20][C:18]1[S:19][C:5]2[C:6]([N:9]3[CH2:14][CH2:13][N:12]([CH3:15])[C:11](=[O:16])[CH2:10]3)=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[C:4]=2[N:17]=1참가 물질
5
실험 절차
From [2-methoxy-5-(4-methyl-3-oxo-piperazin-1-yl)-phenyl]-thiourea with HBr—AcOH (4 equiv.) and DMSO (2.4 equiv.) in AcOH. ES-MS m/e (%): 293 (M+H+, 100).
출처 및 근거
- ORD 기록
- ord-d179064351194b43a86982c843ec674b
- 출처 데이터셋
- uspto-grants-2006_08
- 특허 번호
- US07087761B2
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