Methyl iodide → 7-Methyl-8-oxo-2H,8H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinolin-7-ium iodide

HRID 838929노트

반응식

HRID 838929 반응식
[CH:1]1[CH:2]=[CH:3][C:4]2[C:14](=[O:15])[C:13]3[C:8]4[C:9](=[CH:16][C:17]5[O:21][CH2:20][O:19][C:18]=5[C:7]=4[C:5]=2[CH:6]=1)[CH:10]=[CH:11][N:12]=3.[I:22][CH3:23]>C(Cl)(Cl)Cl>[CH3:23][N+:12]1[CH:11]=[CH:10][C:9]2[C:8]3=[C:7]([C:18]4[O:19][CH2:20][O:21][C:17]=4[CH:16]=2)[C:5]2[C:4]([C:14](=[O:15])[C:13]=13)=[CH:3][CH:2]=[CH:1][CH:6]=2.[I-:22]

참가 물질

4

반응물 2

HCID 6328Methyl iodideHCID 10144Liriodenine2회

생성물 1

HCID 1227727-Methyl-8-oxo-2H,8H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinolin-7-ium iodide

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

Liriodenine methiodide was prepared from the liriodenine isolated in accordance with Example 1. A 2.71 gm sample of liriodenine was reflexed in 30 ml of chloroform and then 10 ml of iodomethane was added. After 24 hours at reflux, the solution was cooled, excess iodomethane removed, and the red crystals filtered. Crystallization from methanol yielded 2.24 gm liriodenine methiodide, mp 235 d.

후처리

  1. customisolated in accordance with Example 1
  2. temperatureAfter 24 hours at reflux
  3. temperaturethe solution was cooled
  4. customexcess iodomethane removed
  5. filtrationthe red crystals filtered
  6. customCrystallization from methanol

출처 및 근거

ORD 기록
ord-b406a0fd906441c69e7be19269da442f
출처 데이터셋
uspto-grants-1978_06
특허 번호
US04093717

반응 노트

불러오는 중…