Phenol → 1,1,1-Trichloro-2,2-bis(4-hydroxyphenyl)ethane

HRID 840332

반응식

HRID 840332 반응식
S(=O)(=O)(O)O.[C:6]1([OH:12])[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.O=[CH:14][C:15]([Cl:18])([Cl:17])[Cl:16]>O>[Cl:16][C:15]([Cl:18])([Cl:17])[CH:14]([C:9]1[CH:10]=[CH:11][C:6]([OH:12])=[CH:7][CH:8]=1)[C:9]1[CH:10]=[CH:11][C:6]([OH:12])=[CH:7][CH:8]=1

참가 물질

5

반응물 3

HCID 996PhenolHCID 1118Sulfuric Acid2회HCID 6407Chloral

생성물 1

HCID 763021,1,1-Trichloro-2,2-bis(4-hydroxyphenyl)ethane수율 98.2%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A 4-necked 3-L flask, equipped with a mechanical stirrer, a nitrogen inlet, and thermometer, is charged with 83% sulfuric acid (640 g). To this sulfuric acid, phenol (354 g) is added at 20° C. Chloral (200 g) in an additional funnel is added dropwise to the phenolic stirring mixture. The reaction temperature is maintained below 30° C. After the addition, the mixture is allowed to stir at room temperature for 18 hours, before water (640 g) is added. The resulting mixture is filtered and washed with more water to afford 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane (423 g) as white solids.

후처리

  1. customA 4-necked 3-L flask, equipped with a mechanical stirrer, a nitrogen inlet
  2. temperatureThe reaction temperature is maintained below 30° C
  3. additionAfter the addition
  4. additionis added
  5. filtrationThe resulting mixture is filtered
  6. washwashed with more water

출처 및 근거

ORD 기록
ord-400d79d45a384523bd918e99381092e8
출처 데이터셋
uspto-grants-2002_04
특허 번호
US06365671B1

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