Sodium hydride → HCID 54150769, 화합물

HRID 851813노트

반응식

HRID 851813 반응식
C1(S([CH2:10][CH2:11][CH2:12][CH:13]2[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][C:14]2=O)(=O)=O)C=CC=CC=1.[H-].[Na+]>C(N)CN>[C:13]12[CH2:12][CH2:11][CH:10]=[C:14]1[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH:24]=2

참가 물질

4

반응물 2

HCID 24758Sodium hydrideHCID 205012032-[3-(Benzenesulfonyl)propyl]cyclododecan-1-one

생성물 1

HCID 54150769HCID 54150769, 화합물수율 75%

시약·촉매·용매 1

HCID 3301Ethylenediamine용매

실험 절차

0.720 g (2 mmole) of 2-(3-phenylsulfonyl-prop-1-yl)-cyclododecanone, 0.144 g (6 mmole) of sodium hydride and 10 ml of ethylene-diamine were heated at 100° for 4 hours, then cooled, extracted and finally distilled as indicated hereinabove to afford the desired compound in a 75% yield.

후처리

  1. temperaturecooled
  2. extractionextracted
  3. distillationfinally distilled

출처 및 근거

ORD 기록
ord-89eb25617c464f6d83729bd5bd70a19a
출처 데이터셋
uspto-grants-1983_05
특허 번호
US04386220

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