Hydroxide → ethyl 3-{2-fluoro-4-[({4'-[(4-hydroxy-1-oxidotetrahydro-2H-thiopyran-4-yl)methoxy]-2',6'-dimethylbiphenyl-3-yl}methyl)amino]phenyl}propanoate

HRID 85783

반응식

[CH3:61][N:62]([CH3:63])[CH:64]=[O:65].[CH3:66][CH2:67][O:68][C:69](=[O:70])[CH3:71].[F:1][c:2]1[c:3]([CH2:46][CH2:47][C:48](=[O:49])[O:50][CH2:51][CH3:52])[cH:4][cH:5][c:6]([N:8]([S:9]([c:10]2[cH:11][cH:12][cH:13][cH:14][c:15]2[N+:16]([O-:17])=[O:18])(=[O:19])=[O:20])[CH2:21][c:22]2[cH:23][c:24](-[c:28]3[c:29]([CH3:45])[cH:30][c:31]([O:35][CH2:36][C:37]4([OH:44])[CH2:38][CH2:39][S:40](=[O:43])[CH2:41][CH2:42]4)[cH:32][c:33]3[CH3:34])[cH:25][cH:26][cH:27]2)[cH:7]1.[Li+:60].[OH-:59].[OH2:58].[SH:53][CH2:54][C:55]([OH:56])=[O:57]>>[F:1][c:2]1[c:3]([CH2:46][CH2:47][C:48](=[O:49])[O:50][CH2:51][CH3:52])[cH:4][cH:5][c:6]([NH:8][CH2:21][c:22]2[cH:23][c:24](-[c:28]3[c:29]([CH3:45])[cH:30][c:31]([O:35][CH2:36][C:37]4([OH:44])[CH2:38][CH2:39][S:40](=[O:43])[CH2:41][CH2:42]4)[cH:32][c:33]3[CH3:34])[cH:25][cH:26][cH:27]2)[cH:7]1