홈MCP워크벤치Skills
홈워크벤치알림마이페이지
llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
  1. 홈
  2. /반응

Methanol → (R)-(+)-3,7-dimethyloctanoic acid

HRID 867139
노트
인쇄 미리보기

반응식

HRID 867139 반응식
C([O:3][C:4](=[O:14])[CH2:5][C@H:6]([CH3:13])[CH2:7][CH2:8][CH2:9][CH:10]([CH3:12])[CH3:11])C.CO.C(Cl)(Cl)Cl>[OH-].[Na+]>[CH3:13][C@H:6]([CH2:7][CH2:8][CH2:9][CH:10]([CH3:12])[CH3:11])[CH2:5][C:4]([OH:14])=[O:3]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

5

반응물 3

HCID 887MethanolHCID 6212ChloroformHCID 13191832Ethyl (3R)-3,7-dimethyloctanoate

생성물 1

HCID 13191833(R)-(+)-3,7-dimethyloctanoic acid수율 60%

시약·촉매·용매 1

HCID 14798Sodium Hydroxide용매

실험 절차

Hydrolysis: 400 mg. (2 mmol) of 3(R),7-dimethyl octanoic acid ethyl ester was refluxed in 6N NaOH (1 ml.) and methanol (4 ml.) for 2 hours. It was worked up as in Example 10 to give 207 mg. (60% yield) of 3(R),7-dimethyl octanoic acid (R-(+)-dihydrocitronellic acid), [α]D25 + 6.81° (c=5.039, CHCl3).

후처리

  1. customHydrolysis
  2. customto give 207 mg

출처 및 근거

ORD 기록
ord-98dffc58ad984a2d8ecaea506bc996e6
출처 데이터셋
uspto-grants-1978_07
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US04102909

반응 노트

불러오는 중…

이 페이지에서참가 물질실험 절차후처리출처 및 근거반응 노트