Spermine → (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

HRID 884324

반응식

HRID 884324 반응식
NCCCNCCCCNCCCN.C([O-])(=[O:27])CCCCCCCCCCC.[Na+].[OH-].[Na+].CC(=CCC/C(=C/CO)/C)C.CCCCCCCCCCCCCCCC([O:60][CH2:61][CH:62]([OH:70])[C@H:63]1[O:67][CH2:66][C@H:65]([OH:68])[C@H:64]1[OH:69])=O>C(O)CCCCCCC>[O:27]=[CH:66][C@@H:65]([C@H:64]([C@@H:63]([C@@H:62]([CH2:61][OH:60])[OH:70])[OH:67])[OH:69])[OH:68]

참가 물질

7

반응물 5

HCID 1103SpermineHCID 14798Sodium HydroxideHCID 637566GeraniolHCID 2735067Sodium LaurateHCID 70687305(5xi)-1,4-Anhydro-6-O-hexadecanoyl-D-xylo-hexitol

생성물 1

HCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

시약·촉매·용매 1

HCID 9571-Octanol용매

실험 절차

A composition was prepared by dissolving human insulin with spermine and polyvinylpyrrolidone (PVP-40), sodium dodecanoate (SD) and methylcellulose (MC-400) in DDW containing NaOH. The solution was then lyophilized and suspended with octanol and geraniol in a mixture of medium chain triglyceride (MCT) oil and castor oil, further containing sorbitan monopalmitate (Span-40). Components and concentrations are detailed in Table 4.

후처리

  1. customA composition was prepared
  2. concentrationComponents and concentrations

출처 및 근거

ORD 기록
ord-45a82a040f7f4059a8c318bef89ed52d
출처 데이터셋
uspto-grants-2012_08
특허 번호
US08241670B2

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