Triethylamine → N'-hydroxynonanimidamide
반응식
[CH2:1]([C:9]#[N:10])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].Cl.[NH2:12][OH:13].C(N(CC)CC)C>CCO>[OH:13][NH:12][C:9](=[NH:10])[CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]참가 물질
5
실험 절차
Octyl cyanide (2 g, 14 mmol) and hydroxylamine hydrochloride (2.495 g, 36 mmol) were dissolved in EtOH (10 mL) and treated with triethylamine (5 mL, 36 mmol) at reflux over night. Extraction: AcOEt/water. Silica gel chromatography: heptane/AcOEt 1:2 afforded a white solid (0.65 g, 26%). MS: m/z=173 (M +H).
후처리
- temperatureat reflux over night
- extractionExtraction
출처 및 근거
- ORD 기록
- ord-344e2ede1a55402092f36b2c52f6ed11
- 출처 데이터셋
- uspto-grants-2008_04
- 특허 번호
- US07351700B2
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