Ethyl formate → Ethyl 3-(5,6-dimethyl-3-pyridyl)-2-formylpropionate

HRID 903347노트

반응식

HRID 903347 반응식
[CH3:1][C:2]1[CH:3]=[C:4]([CH2:9][CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH:5]=[N:6][C:7]=1[CH3:8].[CH:16](OCC)=[O:17].[H-].[Na+]>C(COC)OC>[CH3:1][C:2]1[CH:3]=[C:4]([CH2:9][CH:10]([CH:16]=[O:17])[C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH:5]=[N:6][C:7]=1[CH3:8]

참가 물질

5

반응물 3

HCID 8025Ethyl formateHCID 24758Sodium hydrideHCID 14576944Ethyl 3-(5,6-dimethyl-3-pyridyl)propionate

생성물 1

HCID 12783847Ethyl 3-(5,6-dimethyl-3-pyridyl)-2-formylpropionate

시약·촉매·용매 1

HCID 80711,2-Dimethoxyethane용매

실험 절차

Reaction of ethyl 3-(5,6-dimethyl-3-pyridyl)-propionate with ethyl formate and sodium hydride in dimethoxyethane at room temperature gave ethyl 3-(5,6-dimethyl-3-pyridyl)-2-formylpropionate, m.p. 148°-9°.

출처 및 근거

ORD 기록
ord-facfd15b8eb94cdf940ed000bded43fe
출처 데이터셋
uspto-grants-1980_10
특허 번호
US04227000

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