Hydrogen Bromide → 5-((2-Aminoethyl)thiomethyl)thiazole dihydrobromide

HRID 903742노트

반응식

HRID 903742 반응식
O[CH2:2][C:3]1[S:7][CH:6]=[N:5][CH:4]=1.Cl.[NH2:9][CH2:10][CH2:11][SH:12].[BrH:13]>>[BrH:13].[BrH:13].[NH2:9][CH2:10][CH2:11][S:12][CH2:2][C:3]1[S:7][CH:6]=[N:5][CH:4]=1

참가 물질

4

반응물 3

HCID 260Hydrogen BromideHCID 9082Cysteamine HydrochlorideHCID 27632165-Thiazolylmethanol

생성물 1

HCID 205578455-((2-Aminoethyl)thiomethyl)thiazole dihydrobromide

실험 절차

The reaction of 5-hydroxymethylthiazole (2.01 g.) with cysteamine hydrochloride (1.99 g.) in aqueous hydrobromic acid by the method described in Example 1(i)(a) gave 5-((2-aminoethyl)thiomethyl)thiazole dihydrobromide (4.85 g.) m.p. 191°-194° (from methanol).

출처 및 근거

ORD 기록
ord-8f36305cd56a4d05b25ffcb6a89e475b
출처 데이터셋
uspto-grants-1980_10
특허 번호
US04228291

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