Hydrochloric Acid → alpha-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid

HRID 903828

반응식

HRID 903828 반응식
C[O:2][C:3](=[O:16])[CH:4]([NH2:15])[C:5]1[CH:10]=[CH:9][C:8]([OH:11])=[C:7]([CH2:12][O:13][CH3:14])[CH:6]=1.Cl>[OH-].[Na+]>[NH2:15][CH:4]([C:5]1[CH:10]=[CH:9][C:8]([OH:11])=[C:7]([CH2:12][O:13][CH3:14])[CH:6]=1)[C:3]([OH:16])=[O:2]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 53644499(-)-alpha-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid methyl ester

생성물 1

HCID 23329768alpha-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid

시약·촉매·용매 1

HCID 14798Sodium Hydroxide용매

실험 절차

(-)-α-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid methyl ester is dissolved in aqueous 1 N sodium hydroxide and the solution is stirred at 40°-50° C. for 1 hour. The solution is acidified with 6 N hydrochloric acid to a pH of 7. Evaporation of the solvent gives the title compound in a 90% overall yield.

후처리

  1. customEvaporation of the solvent

출처 및 근거

ORD 기록
ord-0da9b64429ad4d63ab131663f2da5919
출처 데이터셋
uspto-grants-1980_10
특허 번호
US04229363

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