Diethyl Oxalate → HCID 178473087, 화합물
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[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:10])[CH3:9])=[CH:4][C:3]=1[C:11]([F:14])([F:13])[F:12].[C:15](OCC)(=[O:21])[C:16]([O:18][CH2:19][CH3:20])=[O:17].[Na]>>[CH2:19]([O:18][C:16](=[O:17])/[C:15](/[OH:21])=[CH:9]/[C:8]([C:5]1[CH:6]=[CH:7][C:2]([F:1])=[C:3]([C:11]([F:12])([F:13])[F:14])[CH:4]=1)=[O:10])[CH3:20]참가 물질
4
실험 절차
In analogy to the procedure described for example 11 a], 1-(4-fluoro-3-trifluoromethyl-phenyl)-ethanone was reacted with diethyl oxalate in the presence of metallic sodium to give (Z)-4-(4-fluoro-3-trifluoromethyl-phenyl)-2-hydroxy-4-oxo-but-2-enoic acid ethyl ester as colorless solid.
출처 및 근거
- ORD 기록
- ord-09b5c003d8cf4b0bb09515f0755ba42c
- 출처 데이터셋
- uspto-grants-2007_09
- 특허 번호
- US07265149B2
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