Ethanol → 7-Ethoxy-3,7-dimethyloctan-1-ol

HRID 918319

반응식

HRID 918319 반응식
[CH2:1]([OH:3])[CH3:2].C([O:7][CH2:8][CH2:9][CH:10]([CH3:17])[CH2:11][CH2:12][CH:13]=[C:14]([CH3:16])[CH3:15])(=O)C.[OH-].[K+].[BH4-].[Na+]>O>[CH2:1]([O:3][C:14]([CH3:16])([CH3:15])[CH2:13][CH2:12][CH2:11][CH:10]([CH3:17])[CH2:9][CH2:8][OH:7])[CH3:2]

참가 물질

6

반응물 4

HCID 702Ethanol3회HCID 9017Citronellyl AcetateHCID 14797Potassium HydroxideHCID 4311764Sodium borohydride

생성물 1

HCID 227497647-Ethoxy-3,7-dimethyloctan-1-ol

시약·촉매·용매 1

HCID 962Water용매

실험 절차

150 grams of mercuric acetate in 400 ml. of dry ethanol is added to 100 g. of 1-acetoxy-3,7-dimethyloct-6-ene (citronellol acetate) in 200 ml. of dry ethanol cooled in an ice bath. The temperature is allowed to come to room temperature by standing overnight. Then the mixture is cooled to 0°, 100 g. of potassium hydroxide in 1.5 l. of ethanol is added followed by addition of 10 g. of sodium borohydride in small portions. After about 30 minutes at 0°, water (100 ml.) is added and mixture left at room temperature for two hours. The mixture is filtered, filtrate concentrated and extracted with ether. The ethereal extract is washed, dried and evaporated to yield 7-ethoxy-3,7-dimethyloctan- 1-ol which is purified by distillation or chromatography.

후처리

  1. customto come to room temperature
  2. temperatureThen the mixture is cooled to 0°
  3. additionfollowed by addition of 10 g
  4. waitAfter about 30 minutes at 0°
  5. waitmixture left at room temperature for two hours
  6. filtrationThe mixture is filtered
  7. concentrationfiltrate concentrated
  8. extractionextracted with ether
  9. extractionThe ethereal extract
  10. washis washed
  11. customdried
  12. customevaporated

출처 및 근거

ORD 기록
ord-8a0a26540959465e8401d681b565e0a9
출처 데이터셋
uspto-grants-1976_07
특허 번호
US03970704

연결된 노트

불러오는 중…