Sodium Hydroxide → HCID 178506294, 화합물

반응식

P(Cl)(Cl)([Cl:3])=O.[F:6][C:7]([F:19])([F:18])[C:8]1[C:16]2[C:11](=[N+:12]([O-])[CH:13]=[CH:14][CH:15]=2)[NH:10][N:9]=1.[OH-].[Na+]>>[Cl:3][C:15]1[CH:14]=[CH:13][N:12]=[C:11]2[NH:10][N:9]=[C:8]([C:7]([F:19])([F:18])[F:6])[C:16]=12

참가 물질

반응물 3

HCID 14798Sodium Hydroxide

HCID 24813Phosphorus oxychloride

HCID 178526242HCID 178526242, 화합물

생성물 1

HCID 178506294HCID 178506294, 화합물수율 27%

반응 조건

온도: 100 °C

실험 절차

Phosphorus oxychloride (76.4 g) was gradually added to compound (1b) (33.2 g), followed by stirring at 100° C. for 1 hr. The reaction solution was poured into ice water, and sodium hydroxide was added thereto to adjust the pH to 10. The precipitate was collected by filtration to obtain compound (1c) (9.76 g, 270) as a light pink solid.