2,6-Lutidine → 2-((2-chloro-5-cyano-3-(hexahydro-1H-pyrrolo[3,2-c]pyridin-5(6H)-yl)phenyl)amino)-4-(cyclopropyl(4-methoxybenzyl)amino)imidazo[2,1-f][1,2,4]triazine-7-carbonitrile

반응식

[Si](OS(C(F)(F)F)(=O)=O)(C)(C)C.[Cl:13][C:14]1[C:19]([NH:20][C:21]2[N:26]=[C:25]([N:27]([CH:37]3[CH2:39][CH2:38]3)[CH2:28][C:29]3[CH:34]=[CH:33][C:32]([O:35][CH3:36])=[CH:31][CH:30]=3)[C:24]3=[N:40][CH:41]=[C:42]([C:43]#[N:44])[N:23]3[N:22]=2)=[CH:18][C:17]([C:45]#[N:46])=[CH:16][C:15]=1[N:47]1[CH2:52][CH2:51][CH:50]2[N:53](C(OC(C)(C)C)=O)[CH2:54][CH2:55][CH:49]2[CH2:48]1.N1C(C)=CC=CC=1C>ClCCl>[Cl:13][C:14]1[C:15]([N:47]2[CH2:52][CH2:51][CH:50]3[NH:53][CH2:54][CH2:55][CH:49]3[CH2:48]2)=[CH:16][C:17]([C:45]#[N:46])=[CH:18][C:19]=1[NH:20][C:21]1[N:26]=[C:25]([N:27]([CH:37]2[CH2:39][CH2:38]2)[CH2:28][C:29]2[CH:30]=[CH:31][C:32]([O:35][CH3:36])=[CH:33][CH:34]=2)[C:24]2=[N:40][CH:41]=[C:42]([C:43]#[N:44])[N:23]2[N:22]=1