2,6-Lutidine → 2,6-Bis(trifluoromethyl)-3-methoxycarbonyl-4-chloropyridine

반응식

[F:1][C:2]([c:3]1[n:4][c:5]([C:14]([F:15])([F:16])[F:17])[cH:6][c:7]([OH:13])[c:8]1[C:9](=[O:10])[O:11][CH3:12])([F:18])[F:19].[P:28]([Cl:29])([Cl:30])([Cl:31])=[O:32].[n:20]1[c:21]([CH3:22])[cH:23][cH:24][cH:25][c:26]1[CH3:27]>>[F:1][C:2]([c:3]1[n:4][c:5]([C:14]([F:15])([F:16])[F:17])[cH:6][c:7]([Cl:30])[c:8]1[C:9](=[O:10])[O:11][CH3:12])([F:18])[F:19]

참가 물질

반응물 3

HCID 79372,6-Lutidine

HCID 24813Phosphorus oxychloride

HCID 178498966Methyl 2,6-bis(trifluoromethyl)-4-hydroxy-3-pyridinecarboxylate

생성물 1

HCID 138828782,6-Bis(trifluoromethyl)-3-methoxycarbonyl-4-chloropyridine

출처 및 근거

ORD 기록: ord-c55ddb731d5240e285b4590ff4706085
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…