Ethanol → HCID 21962448, 화합물

HRID 971427노트

반응식

HRID 971427 반응식
[Na].C(O)C.[Cl:5][C:6]1[CH:11]=[CH:10][C:9]([CH3:12])=[C:8]([N+:13]([O-:15])=[O:14])[CH:7]=1.C([O:18][C:19](=[O:25])[C:20](OCC)=[O:21])C>O>[N+:13]([C:8]1[CH:7]=[C:6]([Cl:5])[CH:11]=[CH:10][C:9]=1[CH2:12][C:20](=[O:21])[C:19]([OH:25])=[O:18])([O-:15])=[O:14]

참가 물질

6

반응물 4

HCID 702Ethanol2회HCID 6975Benzene, 4-chloro-1-methyl-2-nitro-HCID 7268Diethyl OxalateHCID 5360545Sodium

생성물 1

HCID 21962448HCID 21962448, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

To a cooled mixture prepared by adding 13.6 g. of sodium to 300 ml. of ethanol is added a solution of 100 g. of 4-chloro-2-nitrotoluene and 84 g. of diethyloxalate in 150 ml. of ethanol while maintaining the temperature below 20° C. The resulting mixture is refluxed for one hour, cooled, 400 ml. of water added and the resulting mixture refluxed for 90 minutes. The ethanol is then evaporated to a small volume and the resulting precipitate contains tan and black material and the black material is mechanically separated and discarded and the remainder (filtrate plus tan precipitate) used in the next step.

후처리

  1. customTo a cooled mixture prepared
  2. additionby adding 13.6 g
  3. temperatureThe resulting mixture is refluxed for one hour
  4. temperaturecooled
  5. temperaturethe resulting mixture refluxed for 90 minutes
  6. customThe ethanol is then evaporated to a small volume
  7. customblack material and the black material is mechanically separated

출처 및 근거

ORD 기록
ord-2459b4650b8e4ba386a069400ca15ff5
출처 데이터셋
uspto-grants-1979_07
특허 번호
US04160032

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