Nitrobenzene → 1-(4-Methylphenyl)-3-phenylurea
반응식
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)([O-])=O.[C:10]([O-:13])(=O)C.[K+].[Se].[NH2:16][C:17]1[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=1>O1CCCC1>[C:20]1([CH3:23])[CH:21]=[CH:22][C:17]([NH:16][C:10]([NH:1][C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=2)=[O:13])=[CH:18][CH:19]=1참가 물질
6
반응 조건
- 온도
- 180 °C
실험 절차
Ten milliliters of nitrobenzene, 100 milliliters of tetrahydrofuran, 1.0 gram potassium acetate, 1.0 gram selenium and 21.4 grams of p-toluidine are charged to the autoclave which is then flushed and pressured to 800 psig with carbon monoxide. The temperature is raised to 180° C. for one hour giving 1-p-tolyl-3-phenylurea as product.
후처리
- customis then flushed
출처 및 근거
- ORD 기록
- ord-18802182db8c4af2ae36e5ffa8b87fbd
- 출처 데이터셋
- uspto-grants-1977_10
- 특허 번호
- US04052454
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