Hydrochloric Acid → Methyl 3-(4,6-bis(trichloromethyl)-s-triazin-2-yl)benzoate

HRID 973805

반응식

HRID 973805 반응식
[C:1]([C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][CH:12]=1)[C:6]([O:8][CH3:9])=[O:7])#[N:2].[Cl:13][C:14]([Cl:18])([Cl:17])[C:15]#[N:16].[Br-].[Al+3].[Br-].[Br-].[ClH:23]>>[Cl:13][C:14]([Cl:18])([Cl:17])[C:15]1[N:16]=[C:15]([C:14]([Cl:17])([Cl:13])[Cl:23])[N:16]=[C:1]([C:3]2[CH:4]=[C:5]([CH:10]=[CH:11][CH:12]=2)[C:6]([O:8][CH3:9])=[O:7])[N:2]=1

참가 물질

5

반응물 4

HCID 313Hydrochloric AcidHCID 11011TrichloroacetonitrileHCID 83554Benzoic acid, 3-cyano-, methyl esterHCID 166749Bromhydrol

생성물 1

HCID 14572905Methyl 3-(4,6-bis(trichloromethyl)-s-triazin-2-yl)benzoate

실험 절차

Methyl 3-cyanobenzoate (70 pw) are mixed with trichloroacetonitrile (376 pw) and aluminum bromide (13.9 pw) as described in Example 1, step 2, hydrogen chloride gas is added, the mixture is allowed to react and the reaction product is separated. Recrystallization from ethanol gives 160 pw=82% of white crystals of methyl 3-(4,6-bis(trichloromethyl)-s-triazin-2-yl)benzoate. M.p.: 115 to 117° C.

후처리

  1. additionis added
  2. customto react
  3. customthe reaction product is separated
  4. customRecrystallization from ethanol

출처 및 근거

ORD 기록
ord-75d789af17cf41cba765527cdb44a27a
출처 데이터셋
uspto-grants-1991_11
특허 번호
US05064959

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