Carbamic acid, N-methyl-, ethyl ester → Propoxur

HRID 974096

반응식

HRID 974096 반응식
[CH:1]([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[OH:11])([CH3:3])[CH3:2].[CH3:12][NH:13][C:14](=O)[O:15]CC.P(Cl)(Cl)(Cl)=O>ClC(Cl)C>[CH3:12][NH:13][C:14](=[O:15])[O:11][C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=1[O:4][CH:1]([CH3:3])[CH3:2]

참가 물질

5

반응물 3

HCID 7752Carbamic acid, N-methyl-, ethyl esterHCID 209492-IsopropoxyphenolHCID 24813Phosphorus oxychloride

생성물 1

HCID 4944Propoxur

시약·촉매·용매 1

HCID 63651,1-Dichloroethane용매

실험 절차

To a solution of 2-isopropoxyphenol (1.52 g, 0.01 mole) and ethyl N-methylcarbamate (1.03 g, 0.01 mole) in dichloroethane (10 ml, was added phosphoryl chloride (1.54 g, 0.01 mole) and refluxed for six hours. The reaction mixture was worked up as described earlier to give 2-isopropoxyphenyl N-methylcarbamate of the formula (VI) as a solid, crystallised from pet. ether, m.p. 89° C. to 90° C.

후처리

  1. temperaturerefluxed for six hours

출처 및 근거

ORD 기록
ord-d545c77d6ccc48bb9f5fd6d10567cbc7
출처 데이터셋
uspto-grants-1991_11
특허 번호
US05066819

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