Phloroglucinol → 2,4-Dimethyl-1,3,5-benzenetriol

HRID 980312

반응식

HRID 980312 반응식
[C:1]1([CH:9]=[C:7]([OH:8])[CH:6]=[C:4]([OH:5])[CH:3]=1)O.CN(C)[CH:12]=[O:13].P(Cl)(Cl)(Cl)=O.O1CCOC[CH2:21]1>>[OH:8][C:7]1[C:6]([CH3:21])=[C:4]([OH:5])[CH:3]=[C:12]([OH:13])[C:9]=1[CH3:1]

참가 물질

5

반응물 4

HCID 359PhloroglucinolHCID 6228DimethylformamideHCID 24813Phosphorus oxychlorideHCID 312751,4-Dioxane

생성물 1

HCID 782142,4-Dimethyl-1,3,5-benzenetriol

반응 조건

온도
40 °C

실험 절차

0.6 kg of phloroglucinol is dissolved in 1.4 liters of dioxan and a mixture containing 0.8 liters of N,N-dimethylformamide and 0.96 liters of phosphorus oxychloride is added slowly and with vigorous stirring. The addition of the reagent having been completed, the reaction is maintained at 40° C. for 12 hours containing the stirring and then the whole is poured over 10 kg of crushed ice.

후처리

  1. additionis added slowly and with vigorous stirring
  2. additionThe addition of the reagent
  3. additioncontaining the stirring and then the whole

출처 및 근거

ORD 기록
ord-95c952b9479f46159281fca5ca64d23e
출처 데이터셋
uspto-grants-1987_01
특허 번호
US04636569

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