N,N-Dimethylsuccinamic acid → HCID 22507704, 화합물

HRID 985861노트

반응식

HRID 985861 반응식
[CH3:1][N:2]([CH3:10])[C:3](=[O:9])[CH2:4][CH2:5][C:6]([OH:8])=O.CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.C(N(C(C)C)C(C)C)C.[O:44]1[CH2:49][CH2:48][O:47][CH2:46][CH:45]1[C:50]1[C:58]2[S:57][C:56]([NH2:59])=[N:55][C:54]=2[C:53]([O:60][CH3:61])=[CH:52][CH:51]=1>C1COCC1.C(Cl)(Cl)Cl>[O:44]1[CH2:49][CH2:48][O:47][CH2:46][CH:45]1[C:50]1[C:58]2[S:57][C:56]([NH:59][C:6](=[O:8])[CH2:5][CH2:4][C:3]([N:2]([CH3:1])[CH3:10])=[O:9])=[N:55][C:54]=2[C:53]([O:60][CH3:61])=[CH:52][CH:51]=1

참가 물질

7

반응물 4

HCID 75717N,N-Dimethylsuccinamic acidHCID 81531DiisopropylethylamineHCID 9886157Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 22507697(+)-7-[1,4)Dioxan-2-yl-4-methoxy-benzothiazol-2-ylamine

생성물 1

HCID 22507704HCID 22507704, 화합물

시약·촉매·용매 2

HCID 6212Chloroform용매HCID 8028Tetrahydrofuran용매

실험 절차

From N,N-dimethylsuccinamic acid, HATU and N-ethyldiisopropylamine in THF, then treatment with (+)-7-[1,4]dioxan-2-yl-4-methoxy-benzothiazol-2-ylamine. [α]D20=+21.9° (c=1.04, CHCl3), ES-MS m/e (%): 394 (M+H+, 100).

출처 및 근거

ORD 기록
ord-a1e517830a254ecfa0d43c2c7046460c
출처 데이터셋
uspto-grants-2005_03
특허 번호
US06872833B2

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