3-Nonanone → 3-Nonanol

HRID 989728

반응식

HRID 989728 반응식
[CH3:1][CH2:2][C:3](=[O:10])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9].[BH4-].[Na+]>CO>[CH3:1][CH2:2][CH:3]([OH:10])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9]

참가 물질

4

반응물 2

HCID 612353-NonanoneHCID 4311764Sodium borohydride

생성물 1

HCID 122163-Nonanol수율 96.3%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

20.5 g (144 mmol) of 3-nonanone are initially charged in 200 ml of methanol, 5.45 g (144 mmol) of sodium borohydride are added a little at a time at room temperature and the mixture is stirred overnight. The solvent is removed under reduced pressure and the mixture is then acidified and extracted with dichloromethane. The organic phase is dried over sodium sulphate. Removal of the solvent gives 20 g (96%) of a colourless oil.

후처리

  1. customThe solvent is removed under reduced pressure
  2. extractionextracted with dichloromethane
  3. dry with materialThe organic phase is dried over sodium sulphate
  4. customRemoval of the solvent

출처 및 근거

ORD 기록
ord-f63b7042858a417da8139487ee5a4ea2
출처 데이터셋
uspto-grants-2002_10
특허 번호
US06458796B1

연결된 노트

불러오는 중…