4-(tert-Butylaminosulphonyl)benzeneboronic acid → 4-(Aminosulphonyl)benzeneboronic acid

HRID 1003599Notes

Reaction equation

HRID 1003599 reaction equation
C([NH:5][S:6]([C:9]1[CH:14]=[CH:13][C:12]([B:15]([OH:17])[OH:16])=[CH:11][CH:10]=1)(=[O:8])=[O:7])(C)(C)C>C(O)(C(F)(F)F)=O.CCOCC>[NH2:5][S:6]([C:9]1[CH:10]=[CH:11][C:12]([B:15]([OH:17])[OH:16])=[CH:13][CH:14]=1)(=[O:8])=[O:7]

Participants

4

Reactant 1

HCID 221071704-(tert-Butylaminosulphonyl)benzeneboronic acid

Product 1

HCID 223919774-(Aminosulphonyl)benzeneboronic acid

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 6422Trifluoroacetic acidSolvent

Procedure

A solution of 4-t-butylaminosulfonylbenzene boronic acid (500 mg) in TFA (5 mL) was stirred at r.t. for 15 h. The mixture was diluted with ether and the solid material was filtered to provide the title compound.

Workup

  1. filtrationthe solid material was filtered

Sources & evidence

ORD record
ord-07f470340be640ab8eb15f74be1c9dc0
Source dataset
uspto-grants-2000_04
Patent number
US06046217

Reaction notes

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