Hydrochloric Acid → HCID 86587912, compound

HRID 1003684Notes

Reaction equation

HRID 1003684 reaction equation
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][C:11]=1[O:12][CH3:13])[CH:7]=O)[CH3:2].[C:14]([NH:22][OH:23])([CH2:17][C:18]([CH3:21])([CH3:20])[CH3:19])([CH3:16])[CH3:15].Cl>CO>[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([CH:7]=[N+:22]([C:14]([CH2:17][C:18]([CH3:21])([CH3:20])[CH3:19])([CH3:16])[CH3:15])[O-:23])[CH:9]=[CH:10][C:11]=1[O:12][CH3:13])[CH3:2]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 2447283-Ethoxy-4-methoxybenzaldehydeHCID 10034753HCID 10034753, compound

Product 1

HCID 86587912HCID 86587912, compoundYield 60%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of 3-ethoxy-4methoxybenzaldehyde, N-tert-octylhydroxylamine and catalytic amount of HCl in methanol was refluxed for 90 hrs with molecular sieves in a soxhlet for waster removal. The title compound was obtained in 60.0% yield as white powder, m.p. 77.5° C. (Rf =0.40 on a silica gel plate using hexanes:EtOAc, 3:2, v:v, as an eluant).

Sources & evidence

ORD record
ord-cade264bee0c433594b2c5807af98162
Source dataset
uspto-grants-2000_04
Patent number
US06046232

Reaction notes

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