Hydrochloric Acid → HCID 22670916, compound

HRID 1004540Notes

Reaction equation

HRID 1004540 reaction equation
[C:1]1([CH:8]=[CH:7][CH:6]=[C:4]([OH:5])[CH:3]=1)[OH:2].O[CH2:10][C:11]1[C:17](O)=[C:16]([CH2:19][CH3:20])[CH:15]=[C:14]([CH2:21]O)[C:12]=1[OH:13].Cl>O>[OH:2][C:1]1[CH:3]=[C:4]([OH:5])[CH:6]=[CH:7][C:8]=1[CH2:21][C:14]1[CH:15]=[C:16]([CH2:19][CH3:20])[CH:17]=[C:11]([CH2:10][C:6]2[CH:7]=[CH:8][C:1]([OH:2])=[CH:3][C:4]=2[OH:5])[C:12]=1[OH:13]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 5054ResorcinolHCID 18792544HCID 18792544, compound

Product 1

HCID 22670916HCID 22670916, compoundYield 46.6%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

To a 2 liter round bottom flask was added 800 ml of de-mineralized water, 825.0 g resorcinol and 45.58 g of 2,6-bis(hydroxymethyl)-4-ethylresorcinol. 6.5 ml of concentrated hydrochloric acid was added and the mixture stirred overnight at ambient conditions. The reaction mixture was then added to 12 L of de-mineralized water and slowly stirred at room temperature for 24 hours. The precipitate was isolated by vacuum filtration and washed with de-mineralized water. It was air dried for 24 hours and then vacuum oven dried at 60° C. for 18 hours. About 39.3 g of product was obtained having a purity of about 91% as determined by HPLC analysis.

Workup

  1. stirringslowly stirred at room temperature for 24 hours
  2. customThe precipitate was isolated by vacuum filtration
  3. washwashed with de-mineralized water
  4. customdried for 24 hours
  5. customvacuum oven dried at 60° C. for 18 hours

Sources & evidence

ORD record
ord-b2c85e1141274c42bf1f9fb77b359d75
Source dataset
uspto-grants-2000_04
Patent number
US06051358

Reaction notes

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