Allyl isocyanate → HCID 22674417, compound

HRID 1005718Notes

Reaction equation

HRID 1005718 reaction equation
[NH:1]([C:3]1[N:4]=[C:5]([C:12]([C:14]2[S:15][CH:16]=[CH:17][CH:18]=2)=[O:13])[C:6]2[S:11][CH:10]=[CH:9][C:7]=2[N:8]=1)[NH2:2].[CH2:19]([N:22]=[C:23]=[O:24])[CH:20]=[CH2:21]>C1COCC1>[CH2:19]([NH:22][C:23]([NH:2][NH:1][C:3]1[N:4]=[C:5]([C:12]([C:14]2[S:15][CH:16]=[CH:17][CH:18]=2)=[O:13])[C:6]2[S:11][CH:10]=[CH:9][C:7]=2[N:8]=1)=[O:24])[CH:20]=[CH2:21]

Participants

4

Reactant 2

HCID 15123Allyl isocyanateHCID 22674428HCID 22674428, compound

Product 1

HCID 22674417HCID 22674417, compoundYield 68%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A mixture of 2-hydrazinothieno[3,2-d]pyrimidin-4-yl 2-thienylmethanone (100 mg, 0.36 mmol) and THF (5 mL) was treated with allyl isocyanate (32 μl, 0.36 mmol), stirred at room temperature for 1 h and filtered to give the title compound (88 mg, 68%) as a yellow solid.

Workup

  1. filtrationfiltered

Sources & evidence

ORD record
ord-920c89a828734e7990aed4e5e0eca1f1
Source dataset
uspto-grants-2004_09
Patent number
US06787541B1

Reaction notes

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