Bicarbonate Ion → tert-Butyl (1R*,4R*)-4-(nicotinamido)cyclohexylcarbamate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]1[CH2:10][CH2:11][CH:12]([NH2:15])[CH2:13][CH2:14]1.[CH2:25]([N:26]=[C:27]=[N:28][CH2:29][CH2:30][CH2:31][N:32]([CH3:33])[CH3:34])[CH3:35].[CH3:51][N:52]([CH3:53])[CH:54]=[O:55].[Na+:46].[OH:36][n:37]1[c:38]2[cH:39][cH:40][cH:41][cH:42][c:43]2[n:44][n:45]1.[OH:47][C:48](=[O:49])[O-:50].[n:16]1[cH:17][c:18]([C:22](=[O:23])[OH:24])[cH:19][cH:20][cH:21]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]1[CH2:10][CH2:11][CH:12]([NH:15][C:22]([c:18]2[cH:17][n:16][cH:21][cH:20][cH:19]2)=[O:23])[CH2:13][CH2:14]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-10af2dfbbfe84712ac48d92160744375
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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