Dichloromethane → 5-Cyclohex-1-enyl-3-[(1-isobutyryl-piperidin-4-yl)-(trans-4-methyl cyclohexanecarbonyl)-amino]-thiophene-2-carboxylic acid methyl ester
Reaction equation
[C:39]([CH:40]([CH3:41])[CH3:42])(=[O:43])[Cl:44].[CH3:1][O:2][C:3](=[O:4])[c:5]1[s:6][c:7]([C:26]2=[CH:27][CH2:28][CH2:29][CH2:30][CH2:31]2)[cH:8][c:9]1[N:10]([CH:11]1[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]1)[C:17](=[O:18])[CH:19]1[CH2:20][CH2:21][CH:22]([CH3:25])[CH2:23][CH2:24]1.[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[Cl:45][CH2:46][Cl:47]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[s:6][c:7]([C:26]2=[CH:27][CH2:28][CH2:29][CH2:30][CH2:31]2)[cH:8][c:9]1[N:10]([CH:11]1[CH2:12][CH2:13][N:14]([C:39]([CH:40]([CH3:41])[CH3:42])=[O:43])[CH2:15][CH2:16]1)[C:17](=[O:18])[CH:19]1[CH2:20][CH2:21][CH:22]([CH3:25])[CH2:23][CH2:24]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-089fe7b4595e4f09ab69180fb252cc0f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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