反应详情

温度

110 °C

The product from example 1 step c) (2.0 g) and the product from example 25 step d) (1.3 g) in a solvent of NMP (10 ml) containing Hunigs base (3 ml) was heated at 110° C. for 10 hours. The mixture was evaporated to dryness and purified (SiO2, (1:1) dichloromethane:ethyl acetate as eluant) to give the subtitle compound (1.9 g).

1. customThe mixture was evaporated to dryness
2. custompurified (SiO2, (1:1) dichloromethane:ethyl acetate as eluant)