Methanol → 2-(4-{2-[4-(2-Bromo-5-fluorophenoxy)piperidin-1-yl]pyrimidin-5-yl}-1H-1,2,3-triazol-1-yl)propanoic acid
Reaction equation
[Br:1][c:2]1[c:3]([O:4][CH:5]2[CH2:6][CH2:7][N:8]([c:11]3[n:12][cH:13][c:14](-[c:17]4[n:18][n:19][n:20]([CH:22]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[CH3:28])[cH:21]4)[cH:15][n:16]3)[CH2:9][CH2:10]2)[cH:29][c:30]([F:33])[cH:31][cH:32]1.[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:42][OH:43].[Li+:39].[OH-:40].[OH2:41]>>[Br:1][c:2]1[c:3]([O:4][CH:5]2[CH2:6][CH2:7][N:8]([c:11]3[n:12][cH:13][c:14](-[c:17]4[n:18][n:19][n:20]([CH:22]([C:23](=[O:24])[OH:25])[CH3:28])[cH:21]4)[cH:15][n:16]3)[CH2:9][CH2:10]2)[cH:29][c:30]([F:33])[cH:31][cH:32]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-5132ac06c1e54a52ae7b61bbcea2f882
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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