Hydrochloric Acid → 4-[2-(Trifluoromethyl)phenoxy]piperidin-1-yl-1,3-thiazole-5-carboxylic acid
Reaction equation
[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:35][OH:36].[ClH:29].[F:1][C:2]([c:3]1[c:4]([O:5][CH:6]2[CH2:7][CH2:8][N:9]([c:12]3[s:13][c:14]([C:17](=[O:18])[O:19][CH3:20])[cH:15][n:16]3)[CH2:10][CH2:11]2)[cH:21][cH:22][cH:23][cH:24]1)([F:25])[F:26].[Na+:28].[OH-:27]>>[F:1][C:2]([c:3]1[c:4]([O:5][CH:6]2[CH2:7][CH2:8][N:9]([c:12]3[s:13][c:14]([C:17](=[O:18])[OH:19])[cH:15][n:16]3)[CH2:10][CH2:11]2)[cH:21][cH:22][cH:23][cH:24]1)([F:25])[F:26]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-4cc3c5081a434d47b0b443a72c8ccb00
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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