Hydrochloric Acid → HCID 22666336, compound

HRID 1007897Notes

Reaction equation

HRID 1007897 reaction equation
[CH3:1][N:2]([CH2:6][CH2:7][O:8][CH2:9][CH2:10][C:11]1[CH:12]=[C:13]2[C:18](=[CH:19][CH:20]=1)[N:17]=[CH:16][CH:15]=[N:14]2)[CH2:3][CH2:4][OH:5].[ClH:21]>C(O)C>[ClH:21].[ClH:21].[ClH:21].[CH3:1][N:2]([CH2:6][CH2:7][O:8][CH2:9][CH2:10][C:11]1[CH:12]=[C:13]2[C:18](=[CH:19][CH:20]=1)[N:17]=[CH:16][CH:15]=[N:14]2)[CH2:3][CH2:4][OH:5]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 22666265HCID 22666265, compound

Product 1

HCID 22666336HCID 22666336, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

In 3 mL of ethanol is dissolved 0.23 g of 2-(methyl{2-[2-(6-quinoxalinyl)ethoxy]ethyl}amino)-1-ethanol, to which is added 0.8 mL of 3.8 mol/L solution of dry hydrogen chloride in ethanol. The mixture is stirred at ambient temperature for one hour. By distilling off the solvent under reduced pressure, there is obtained 0.67 g of 2-(methyl{2-[2-(6-quinoxalinyl)-ethoxy]ethyl}amino)-1-ethanol trihydrochloride as an oily product.

Workup

  1. distillationBy distilling off the solvent under reduced pressure

Sources & evidence

ORD record
ord-793bf4a9f14546a5be720fd77669c16a
Source dataset
uspto-grants-2004_09
Patent number
US06797726B1

Reaction notes

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