Thioanisole → HCID 135829388, compound

HRID 1010349Notes

Reaction equation

HRID 1010349 reaction equation
C1(SC)C=CC=CC=1.C([O:16][C:17]1[CH:26]=[C:25]2[C:20]([C:21]([O:27][C:28]3[CH:33]=[CH:32][C:31]([N+:34]([O-:36])=[O:35])=[CH:30][CH:29]=3)=[CH:22][CH:23]=[N:24]2)=[CH:19][C:18]=1[O:37][CH3:38])C1C=CC=CC=1>FC(F)(F)C(O)=O>[CH3:38][O:37][C:18]1[CH:19]=[C:20]2[C:25](=[CH:26][C:17]=1[OH:16])[N:24]=[CH:23][CH:22]=[C:21]2[O:27][C:28]1[CH:29]=[CH:30][C:31]([N+:34]([O-:36])=[O:35])=[CH:32][CH:33]=1

Participants

4

Reactant 2

HCID 7520ThioanisoleHCID 22936514HCID 22936514, compound

Product 1

HCID 135829388HCID 135829388, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Conditions

Temperature
70 °C

Procedure

After adding trifluoroacetic acid (30 ml) and thioanisole (3 ml) to 7-benzyloxy-6-methoxy-4-(4-nitrophenoxy)quinoline (4.0 g), the mixture was heated and stirred at 70° C. for 2 hours.

Workup

  1. temperaturethe mixture was heated

Sources & evidence

ORD record
ord-dfef94103f0742fb9ff1dc1030ea1da0
Source dataset
uspto-grants-2011_07
Patent number
US07973160B2

Reaction notes

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