反应详情

温度

120 °C

A mixture of 2,6-dichloro-1H-purine (5 g) and ammonia solution (79.2 mL, 2M in (isopropanol) was stirred and heated at 120° C. in an autoclave overnight. The reaction was cooled and concentrated in vacuo to give the title compound as an off-white solid in quantitative yield.

1. temperatureThe reaction was cooled
2. concentrationconcentrated in vacuo