反应详情

2-Butoxy-8-methoxy-9-(tetrahydrofuran-3-ylmethyl)-9H-purin-6-amine (Isomer 2, 178 mg) was suspended in methanol (2 ml) and 4N HCl in dioxan (1 ml) added. The resulting clear solution was stripped and the residue treated with water and basified with saturated aqueous sodium bicarbonate. The solid obtained was filtered, washed with water and dried to give the title compound (isomer 2), yield 72 mg (low due to mechanical losses).

1. customThe solid obtained
2. filtrationwas filtered
3. washwashed with water
4. customdried