反应详情

290 mg (1.07 mmol) of ethyl (R)-(1-tert-butoxycarbonylpiperidin-3-yl)acetate (Example 17A) are stirred with 2 ml of dichloromethane and 2 ml of trifluoroacetic acid at RT for 1 h. The volatile components are removed on a rotary evaporator and the residue is dried under high vacuum. The resulting oil (301 mg, 99% of theory) is reacted further as it is.

1. customThe volatile components are removed on a rotary evaporator
2. customthe residue is dried under high vacuum
3. customThe resulting oil (301 mg, 99% of theory) is reacted further as it