Trifluoroacetic acid → HCID 67313368, compound

HRID 1012641Notes

Reaction equation

HRID 1012641 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]2[CH:14]=[CH:13][C:12]([C:15]([C:17]3[CH:22]=[C:21]([O:23]CC4C=CC(OC)=CC=4)[CH:20]=[CH:19][C:18]=3[CH3:33])=[O:16])=[C:11]([N+:34]([O-:36])=[O:35])[CH:10]=2)=[C:4]([CH3:37])[CH:3]=1.C(O)(C(F)(F)F)=O>C(Cl)Cl>[F:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]2[CH:14]=[CH:13][C:12]([C:15]([C:17]3[CH:22]=[C:21]([OH:23])[CH:20]=[CH:19][C:18]=3[CH3:33])=[O:16])=[C:11]([N+:34]([O-:36])=[O:35])[CH:10]=2)=[C:4]([CH3:37])[CH:3]=1

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 58677612HCID 58677612, compound

Product 1

HCID 67313368HCID 67313368, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Compound 298 (0.57 g, 1.14 mmol) was dissolved in CH2Cl2 (10 mL) and CF3COOH (10 mL) was added. The reaction mixture was stirred at room temperature for 2 h after which the solvent was concentrated. The solid was recrystallized from CH2Cl2. This gave the title compound as a solid.

Workup

  1. concentrationwas concentrated
  2. customThe solid was recrystallized from CH2Cl2

Sources & evidence

ORD record
ord-d3b24bcccea84f30ac142758eebf68c0
Source dataset
uspto-grants-2011_07
Patent number
US07977387B2

Reaction notes

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