反应详情

Starting from 27.8 g (137.1 mmol) of 3-bromo-2-fluorobenzaldehyde, by general method A with 8.2 g (205.7 mmol) of sodium hydride (60% in liquid paraffin) and 16.0 g (150.9 mmol) of methyl mercaptoacetate, 20.57 g of a mixture of the title compound and the corresponding acid (about 1:1) is obtained.