Acetic Anhydride → Tert-butyl 2-acetamido-1-(4-chlorophenyl)ethylcarbamate

HRID 101272Notes

Reaction equation

HRID 101272 reaction equation
[CH2:19]([N:20]([CH:21]([CH3:22])[CH3:23])[CH:24]([CH3:25])[CH3:26])[CH3:27].[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:28][C:29](=[O:30])[O:31][C:32](=[O:33])[CH3:34].[NH2:1][CH2:2][CH:3]([c:4]1[cH:5][cH:6][c:7]([Cl:10])[cH:8][cH:9]1)[NH:11][C:12]([O:13][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:18]>>[NH:1]([CH2:2][CH:3]([c:4]1[cH:5][cH:6][c:7]([Cl:10])[cH:8][cH:9]1)[NH:11][C:12]([O:13][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:18])[C:29]([CH3:28])=[O:30]

Participants

5

Reactant 4

HCID 7918Acetic AnhydrideHCID 8028TetrahydrofuranHCID 81531DiisopropylethylamineHCID 57750386tert-butyl N-[2-amino-1-(4-chlorophenyl)ethyl]carbamate

Product 1

HCID 57750416Tert-butyl 2-acetamido-1-(4-chlorophenyl)ethylcarbamate

Sources & evidence

ORD record
ord-d6d5bc5b38ee470e853a9d629828a22f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…