Trifluoroacetic acid → HCID 67207770, compound

HRID 1013425Notes

Reaction equation

HRID 1013425 reaction equation
C([O:5][C:6]([CH:8]1[CH:12]([C:13]2[S:17][C:16]3[CH:18]=[CH:19][CH:20]=[CH:21][C:15]=3[CH:14]=2)[CH2:11][N:10]([CH:22]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH3:23])[CH2:9]1)=[O:7])(C)(C)C.C(O)(C(F)(F)F)=O>ClCCl>[S:17]1[C:13]([CH:12]2[CH2:11][N:10]([CH:22]([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[CH3:23])[CH2:9][CH:8]2[C:6]([OH:7])=[O:5])=[CH:14][C:15]2[CH:21]=[CH:20][CH:19]=[CH:18][C:16]1=2

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 67207033HCID 67207033, compound

Product 1

HCID 67207770HCID 67207770, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The product from step b) (2.0 g, 0.0077 mol) was dissolved in 20 mL dichloromethane and was treated with 10 mL of TFA and stirred for 2 hours at room temperature. The solvent was evaporated in vacuo to give the crude subtitle compound that was used in the next step without further purification. MS calculated for C21H21NO2S +H: 352, observed: 352.

Workup

  1. customThe solvent was evaporated in vacuo

Sources & evidence

ORD record
ord-0d6ed1d22f4f4f5282f66526ea180c95
Source dataset
uspto-grants-2011_07
Patent number
US07981919B2

Reaction notes

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